Different types of magnesium
Read more about the literature and background of the different types of magnesium.
Magnesium chloride is most frequently utilized for transdermal absorption, which is the absorption via the skin, while being readily absorbed through the gastrointestinal system as well. Since ancient times, this type of supplementation has been used. The Dead Sea was already used by the Romans for therapeutic bathing. Therefore, the treatments found in salt springs have been used for many years and are still widely accepted as essential to good health and wellbeing.
Transdermal magnesium has advanced in the home environment since 2008.
This is caused by a variety of interrelated factors:
- Publications on the superior bioavailability of transdermal magnesium chloride. 
- Greater awareness about structural magnesium deficiency among large parts of the world population. 
- Exploitation of magnesium sources for supplementation.
The Dead Sea and the Salt Lakes in the United States have historically been true of the last statement. The availability of magnesium from the Zechstein deposit starting in 2008 was a significant improvement. The predicate “from the purest source in the world” was immediately given to this magnesium chloride, and it has since increased.
More and more individuals are adopting this magnesium and the transdermal absorption form, despite the fact that there is currently no convincing scientific data for the extent of transdermal absorption. It surely helps that it is a pure natural product with a special blend of trace elements in addition to a high amount of magnesium chloride. Perhaps more significant are:
- Less chance of stomach/intestinal complaints
- The experienced (direct) effect
For oral use, the so-called “organic” forms are dominant in the range. In addition, the “inorganic” ion to which the magnesium is bound has been replaced in a process by a substance from living nature, an acid or an amino acid. From this manufactured compound there is then in pill or powder form a better absorption in the body compared to the natural inorganic forms. This with the exception of magnesium chloride and, to a somewhat lesser extent, magnesium sulphate.
The latter form is used medicinally (intravenously). The use of magnesium sulphate instead of the body’s own magnesium chloride has more historical than medical/biological reasons.
Within the organic forms for oral use, the citrate compound is one of the oldest and most widely used. The citrus connection is logical and the effect on muscles and joints in particular is good. It also provides more energy. A disadvantage is that gastrointestinal problems can arise.
The latter is less the case with magnesium bisglycinate. This special amino acid compound is very well absorbed. The gut-brain axis is attributed an important role in its operation. This explains that it mainly has a positive effect on memory, concentration, nervous system, learning ability and mental relaxation (anti stress).
 See, among others, “The Magnesium Miracle” by Dr. Garolyne Dean and “Transdermal Magnesium Therapy” by Dr. Mark Sircus.
 J.J. DiNicolantonio, “Subclinical magnesium deficiency: a principal driver of cardiovascular disease and a public health crisis” Open Heart 2018, 5.1
 Schwalfenberg, G.K., Genuis, S.J. “The importance of magnesium in clinical Healthcare” in Scientifica 2017
 Durlach,J, ea “Magnesium chloride or magnesium sulphate a genuine question” in Magnesium Research, 2005 18.
 Hartle, J.W., ea “Development of a model for In Vitro Comparative absorption of magnesium…”The Faseb journal, April 2016.