But what is Histamine and what’s it’s Function?
Histamine is an organic nitrogen compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.
Histamine triggers the inflammatory response. As part of an immune response to foreign pathogens, histamine is produced by basophils and by mast cells found in nearby connective tissues.
Histamine increases the permeability of the capillaries to white blood cells and some proteins, to allow them to engage pathogens in the infected tissues.
Histamine is found in mast cells. It’s released to help fight infection/illness/injury, keep us awake, regulate our hormones, run our digestive system and as a neurotransmitter.
Some people have unstable mast cells that release too much of it, or they just have too many mast cells.
Some people have allergies which means they also have too much histamine at times.
Others have too little of the histamine lowering enzymes diamine oxidase (DAO).
An excess of histamine is involved in: allergies, histamine intolerance, mast cell activation, mastocytosis and a number of other medical conditions.
Other than being found in the body, histamine is also found in food!
Some foods contain it, while others trigger its release.
We know that already…
Ok… in simple words….
If and when your immune system reacts, forever what reason, certain cells release histamine. A very normal reaction of your immune system.
It reacts for a good reason:
It’s released to help fight infection, illness, an injury, keep us awake, regulate our hormones, run our digestive system and as a neurotransmitter. All very helpfull!
Things go wrong when we have too much of it or too little “breakdown helpers” we call enzymes….